WHAT IS NEUROFIX?
Neurofix is a Biotech company dedicated to the research of effective drugs against neuropathic pain, currently, there is no effective reference treatment for this type of ailments. In addition to its main line, Neurofix also works in the research of drugs against spinal cord injuries and improvement of sleep. Neurofix is carrying out the pharmaceutical development of NFX88, a drug with a novel mechanism of action for the treatment of neuropathic pain associated with spinal cord injury (first-in-class) that aims to be the most effective for the control of this disease (best -in-class).
Currently, the company has its first drug: NFX88 in phase 2a, which is being studied in patients for the tolerability, safety and efficacy of the drug for the treatment of neuropathic pain associated with spinal cord injury. Likewise, the second drug in the pipeline is in phase 1 and is NFX81, which also focuses on spinal cord injuries.
The company's commercial strategy is based on obtaining orphan drug status, as well as standard-of-care or reference treatment status. To this end, the company carries out its clinical trials together with the drugs currently used against this ailment, such as Pregabalin, a neurotransmitter inhibitor.
BUSINESS MODEL
Neurofix's business plan mainly contemplates the application of a licensing and royalty model whereby an initial payment will be charged for the assignment of the commercial exploitation rights of the product based on the units sold in a model of exclusivity by territory.
In this way the company retains the intellectual property (IP) and, in addition to the upfront payment, would receive a royalty on gross sales which normally ranges between 10% and 30%.
Alternatively, if the company's situation allows, a licensing model, including the supply of the product, could be considered. In this case, Neurofix would not charge a royalty but a mark-up on manufacturing costs, which for this type of product can be up to 35% of the sales price of the licensee company, equivalent to a 20% royalty on sales.
DESTINATION OF THE FUNDS
The financing round proposed by Neurofix at this moment is up to a maximum of 1.125.000€, being the initial size of the round 900.000€.
These funds will be used primarily for the completion of phase IIa and the beginning of phase IIb for the NFX88 product.
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Investor Session
The investments and reservations made to date in this project are shown below.
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Investor from Madrid, España | Has invested |
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Investor from Madrid, España | Has invested |
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Investor from Barcelona, España | Has invested |
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Investor from Barcelona, España | Has invested |
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Investor from Madrid, España | Has invested |
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Investor from Madrid, España | Has invested |
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Investor from Córdoba, España | Has invested |
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Company from Madrid, España | Has invested |
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Investor from A Coruña, España | Has invested |
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Investor from Alicante, España | Has invested |
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Investor from Madrid, España | Has invested |
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Investor from Madrid, España | Has invested |
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Investor from Barcelona, España | Has invested |
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Investor from Barcelona, España | Has invested |
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Investor from Madrid, España | Has invested |
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Investor from Asturias, España | Has invested |
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Investor from Madrid, España | Has invested |
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Investor from Murcia, España | Has invested |
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Investor from Barcelona, España | Has invested |
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Investor from Madrid, España | Has invested |
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Investor from Madrid, España | Has invested |
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Investor from Madrid, España | Has invested |
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Investor from Madrid, España | Has invested |
The investments and reservations made by members of the Fellow Funders team are reported below.
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Fellow Funders team member | Has invested |
Company Neurofix SA
Miguel Ángel Avila Santiago
Developers
Miguel Ángel Ávila Santiago is since April 2016 CEO of Neurofix, a biotech company that develops drugs focused on the Central Nervous System. He holds a degree in Agricultural Engineering from the University of Salamanca, a master's degree in R&D management GESTIDI and an MBA. He has developed throughout his career more than seventy European and national R&D projects. Before joining Neurofix, he worked as R&D&I director, advisor and manager in organizations such as FEPEX (the most important fruit and vegetable export federation in Spain) and Oblanca (the second largest meat group in Castilla y León). He has also held positions in companies such as Tragsa, Instituto Tecnológico y de Energías Renovables (ITER) and Instituto Tecnológico Agrario de Castilla y León (Itacyl). He is a member of the scientific advisory board of FEDME, and was a member of the board of directors of the Colegio Oficial de Ingenieros Técnicos Agrícolas y Graduados en Ingeniería de la Rama Agrícola de Castilla Duero (Official Association of Agricultural Technical Engineers and Graduates in Agricultural Engineering of Castilla Duero). He is passionate about the mountains, has more than 700 ascents to his credit and has published five books. For several legislatures he was mayor of Mozodiel de Sanchinigo (Salamanca) and has given lectures at various Spanish universities.
Mario is the founding partner of the Venture Builder specialized in life sciences Nowture, he has a degree in Business Administration & Management with more than 15 years of experience in the pharmaceutical sector, holding positions as director or member of the board, oriented to the organic and inorganic growth of companies.
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